KeyserLab

Recent Research Highlights

Y. Li, S. C. Meng, Y. Wang, C. M. Platnich, M. K. Earle, E. Mylona, P. Naydenova, S. Baker, J. Zhu and U. F. Keyser.
Nanopore detection of single-nucleotide RNA mutations and modifications with programmable nanolatches.
Nature Nanotechnology, 20:7014−7024, 2025. [ DOI | html ]

F. Zheng, A. Suma, C. Maffeo, K. Chen, M. Alawami, J.J. Sha, A. Aksimentiev, C. Micheletti, U. F. Keyser.
Torsion-Driven Plectoneme Formation During Nanopore Translocation of DNA Polymers.
Physical Review X, 15:031041,2025. [DOI| http ]

S. E. Sandler, N. Weckman, S. Yorke, A. Das, K. Chen, R. Gutierrez, and U. F. Keyser.
Sensing the DNA-mismatch tolerance of catalytically inactive Cas9 via barcoded DNA nanostructures in solid-state nanopores.
Nature Biomedical Engineering, 8:335, 2024. [ DOI | html ]

F. Bošković, J. Zhu, R. Tivony, A. Ohmann, K. Chen, M. Alawami, M. Djordjevic, N. Ermann, J. Pereira Dias, M. Fairhead, M. Howarth, S. Baker, and U. F. Keyser.
Simultaneous identification of viruses and viral variants with programmable DNA nanobait.
Nature Nanotechnology, 18:290–298, 2023. [ http ]

K. Chen, A. Choudhary, S. E. Sandler, C. Maffeo, C. Ducati, A. Aksimentiev, and U. F. Keyser.
Super-Resolution Detection of DNA Nanostructures Using a Nanopore.
Advanced Materials, 35(12): 2207434, 2023. [ http ]

F. Bošković and U. F. Keyser.
Nanopore microscope identifies RNA isoforms with structural colors.
Nature Chemistry, 14:1258-1264, 2022. [ DOI | http ]

Preprints: arxived, submitted, accepted, or in press

F. Bošković, S. Sandler, S. Brauburger, Y. Shui, B. Kumar, J. Pereira Dias, P. Naydenova, J. Zhu, S. Baker, and U. F. Keyser.
Modular RNA:DNA nanostructures enable nanopore profiling of ribosomal RNA processing and rRNA variants.
Preprint, submitted, 2025. [ http ]

Z. Liu, Y. Li, Y. Liu, Y. Nie, R. Hu, U. F. Keyser, K. Chen.
Reconfigurable Multichannel Glass Nanopores Speed up DNA and MicroRNA Detection.
Submitted, 2025.

F. Zheng, Z. Wang, A. Bai, R. Hu, X. Sun, J. Sha, Q. Zhao, K. Chen, and U. F. Keyser.
Choosing Your Nanopore Sensor: Glass or SiNx?.
submitted, 2025.

G. Patino-Guillen, J. Pešoviković, M. Paniković, M. Earle, A. Ninkoviković, S. Petrušca, D. Savić Pavićević, U. F. Keyser, and F. Bošković.
Quantification of disease-associated RNA tandem repeats by nanopore sensing.
submitted, 2025.

G. Patino-Guillen, T. T. Schmidt, J.J. Baumberg, J. Szostak, U. F. Keyser, and F. Bošković.
Nanopore-based profiling of PEGylation in nucleic acid therapeutics.
Preprint, submitted, 2025. [ http ]

A. L. Thorneywork, J. Gladrow, U. F. Keyser, M. E. Cates, R. Adhikari, J. Kappler.
Resolution dependence of most probable pathways with state-dependent diffusivity.
Preprint, under revision, 2024. [ http ]

J. Ermann, K. Chen, and U. F. Keyser.
Bayesian inference for nanopore data analysis.
Preprint, 2019. [ http ]

N. A. W. Bell and U. F. Keyser.
Direct Measurement reveal non-Markovian fluctuations of DNA threading through a nanopore.
Preprint, 2016. [ http ]

Published

S. Brauburger and U. F. Keyser.
A biophysicist’s guide to translocation of double-stranded nucleic acids through solid-state nanopores.
Physics of Life Reviews, 1855, 2026. [DOI| http ]

M. K. Earle, M. Alawami, R.-E. Alexii, S. Brauburger , U. F. Keyser, and C. Platnich.
Quantifying RNA Degradation with Single-Molecule Nanopore Sensing.
Analytical Chemistry, 97:23841-23847, 2025. [DOI| http ]

T. T. Schmidt, M. K. Earle, G. Patino-Guillen, Y. Li, R.E. Alexii, J. J. Bauberg, U. F. Keyser, and C. M. Platnich.
Supramolecular Interactions Modulate RNA:DNA Folding Observed via Nanopore Sensing.
Angewandte Chemie, 64:e20258917, 2025. [DOI| http ]

K. Loha. T. Boonkoom, H. Pitakjakpipop, I. Alam, A. Treetong, P. Boonbanjong, I. Chatnuntawech, S. Teerapittayanon, U. F. Keyser, A. Schulte, D. Japrung.
Structural and Kinetic Profiling of Rolling Circle Amplification via Solid-State Nanopore Sensing Using miR-21 as a Model.
ACS Sensors, 10:7014−7024, 2025. [DOI| http ]

M. Fletcher, Y. Elani, U. F. Keyser, and R. Tivony.
Giant unilamellar vesicles as a model system for studying ion transport.
Biophysical Reviews, published online, 2025. [DOI | http ]

I. Mohora, G. Patino Guillen, K. Neis, J. Valero, U. F. Keyser, and F. Bošković.
Programmable RNA Nanostructures Enable Nanopore Detection of Cotranscriptionally Introduced RNA Modifications.
Nano Letters, 25:12184−12192, 2025. [DOI | http ]

R. Horne, S. E. Sandler, M. Vendruscolo, and U. F. Keyser.
Detection of protein oligomers with nanopores.
Nature Reviews Chemistry, 9:224–240, DOI | http ]

S. Rocchetti, T. Schmidt, U. F. Keyser, and J. J. Baumberg.
Controlling Single-Emitter Strong Coupling by Sculpting DNA Dye Scaffolds in NPoM Cavities.
The Journal of Physical Chemistry C, 129:3684−3689, 2025. [ DOI | http ]

F. Bošković, C. Maffeo, G. Patino-Guillen, R. Tivony, A. Aksimentiev, U. F. Keyser.
Nanopore Translocation Reveals Electrophoretic Force on Noncanonical RNA:DNA Double Helix.
ACS nano, 18(23):15013-15024, 2024. [ DOI | http ]

C. M. Platnich, M. K. Earle, U. F. Keyser.
Chemical Annealing Restructures RNA for Nanopore Detection.
JACS, 146(19):12919-12924, 2024. [ DOI | html ]

G. Patino Guillen, J. Pešović, D. Savić-Pavićević, F. Bošković, and U. F. Keyser.
Single-Molecule RNA Sizing Enables Quantitative Analysis of Alternative Transcription Termination.
Nature Communications, 15:1699, 2024. [ DOI | html ]

F. Zheng, M. Alawami, J. Zhu, C. Platnich, J. Sha, U. F. Keyser, K. Chen.
DNA Carrier-Assisted Molecular Ping-Pong in an Asymmetric Nanopore.
Nano Letters, 23(23): 11145-11151, 2023. [ DOI | html ]

S. E. Sandler, R. I. Horne, S. Rocchetti, R. Novak, N.-S. Hsu, M. Castellana Cruz, Z. F. Brotzakis, R. C. Gregory, S. Chia, G. J. L. Bernardes, U. F. Keyser, M. Vendruscolo.
Multiplexed Digital Characterization of Misfolded Protein Oligomers via Solid-State Nanopores.
JACS, 145(47): 25776-25788, 2023. [ DOI | html ]

S. L. Williams, C. S. Casas-Delucchi, F. Raguseo, D. Guneri, Y. Li, M. Minamino, E. E. Fletcher, J. T. P. Yeeles, U. F. Keyser, Z. A. E. Waller, M. Di Antonio, G. Coster.
Replication-induced DNA secondary structures drive fork uncoupling and breakage.
The EMBO Journal, 42:e114334, 2023. [ DOI | html ]

Y. Li, S. E. Sandler, U. F. Keyser, and J. Zhu.
DNA volume, topology, and flexibility dictate nanopore current signals.
Nano Letters, 23(15): 7054-7061, 2023. [ DOI | html ]

J. Mc Hugh, S. Makarchuk, D. Mozheiko, A. Fernandez-Villegas, G. S. Kaminski-Schierle, C. F. Kaminski, U. F. Keyser, D. Holcman, and N. Rouach.
Diversity of dynamic voltyage patterns in neuronal dendrites revealed by nanopipette electrophysiology.
Nanoscale, 15(29): 12245-12254, 2023. [ DOI | html ]

S. Rocchetti, A. Ohmann, R. Chikkaraddy, G. Kang, U. F. Keyser, and J. J. Baumberg.
Amplified Plasmonic Forces from DNA Origami-Scaffolded Single Dyes in Nanogaps .
Nano Letters, 23(13): 5959-5966, 2023. [ DOI | html ]

S. M. Leitao, V. Navikas, H. Miljkovic, B. Drake, S. MArion, G. Pistoletti Blanchet, K. Chen, U. F. Keyser, A. Kuhn, G. E. Fatner, and A. Radenovic.
Spatially multiplexed single-molecule translocations through a nanopore at controlled speeds .
Nature Nanotechnology, 18: 1078-1084, 2023. [ Biorxiv | html ]

J. Zhu, J. , R. Tivony, F. Bošković, J Pereira-Dias, S. E. Sandler, S. Baker, and U. F. Keyser*.
Multiplexed Nanopore-Based Nucleic Acid Sensing and Bacterial Identification Using DNA Dumbbell Nanoswitches.
JACS, 145(22): 12115–12123, 2023. [ DOI | html ]

A. Doricchi, C. M. Platnich, A. Gimpel, F. Horn, M. Earle, G. Lanzavecchia, A. L. Cortajarena, L. M. Liz-Marzan, N. Liu, R. Heckel, R. N. Grass, R. Krahne, U. F. Keyser, and D. Garoli.
Emerging Approaches to DNA Data Storage: Challenges and Prospects.
ACS nano, 16(11):17552-17571, 2022. [ DOI | html ]

J. Zhu, J. Kong, U. F. Keyser, and E. Wang.
Parallel DNA circuits by autocatalytic strand displacement and nanopore readout.
Nanoscale, 14:15507-15515, 2022. [ DOI | html ]

M. Fletcher, J. Zhu, R. Rubio-Sanchez, Sandler S., K. Al Nahas, L. Di Michele, U. F. Keyser, and R. Tivony.
DNA-Based Optical Quantification of Ion Transport across Giant Vesicles.
ACS Nano, 16(10):17128-17138, 2022. [ DOI | http ]

F. Bošković and U. F. Keyser.
Nanopore microscope identifies RNA isoforms with structural colors.
Nature Chemistry, 14:1258-1264, 2022. [ DOI | http ]

K. Al Nahas, M. Fletcher, K. Hammond, C. Nehls, J. Cama, M. G. Ryadnov, and U. F. Keyser.
Measuring thousands of single vesicle leakage events reveals the mode of action of antimicrobial peptides.
Analytical Chemistry, 94(27):9530-9539, 2022. [ DOI | http ]

S. F. Knowles, M. Fletcher, J. Mc Hugh, M. Earle, U. F. Keyser, and A. L. Thorneywork.
Observing capture with a colloidal model membrane channel.
Journal of Physics: Condensed Matter, 34:344001, 2022. [ DOI | http ]

J. Zhu, F. Bošković, and U. F. Keyser.
Split G-quadruplexes enhance nanopore signals for simultaneous identification of multiple nucleic acids.
Nano Letters, 22(12):4993-4998, 2022. [ DOI | http ]

R. Tivony, M. Fletcher, and U. F. Keyser.
Quantifying proton-induced membrane polarization in single biomimetic giant vesicles.
Biophys. J., 121(12):2223-2232, 2022. [ DOI | http ]

M. F. Alawami, F. Bošković, Z. Zhu, K. Chen, S. E. Sandler, and U. F. Keyser.
Lifetime of glass nanopores in a PDMS chip for single-molecule sensing.
iScience, 25(5):104191, 2022. [ DOI | http ]

J. Mc Hugh, K. Thorneywork, A. L. Andresen, and U. F. Keyser.
3D flow field measurements outside nanopores.
Rev. Sci. Instr., 93(5):054106, 2022. [ DOI | http ]

F. Bošković and U. F. Keyser.
News and Views: Toward single-molecule proteomics.
Science, 374(6574):1443-1444, 2022. [ DOI | http ]

O. Vanderpoorten, A. N. Babar, G. Krainer, R. P. B. Jacquat, P. K. Challa, Q. Peter, Z. Toprakcioglu, C. K. Xu, U. F. Keyser, J. J. Baumberg, C. F. Kaminski, and T. P. J. Knowles.
Nanofluidic Traps by Two-Photon Fabrication for Extended Detection of Single Macromolecules and Colloids in Solution.
ACS Applied Nano Materials, 5(2):1995-2005, 2022. [ DOI | http ]

D. Morzy, M. Schaich, and U. F. Keyser.
A Surfactant Enables Efficient Membrane Spanning by Non-Aggregating DNA-Based Ion Channels.
Molecules, 27(2):578, 2022. [ DOI | http ]

J. Gorman, S. R. E. Osborne, A. Sridhar, R. Pandya, P. Budden, A. Ohmann, N. A. Panjwani, Y. Liu, J. L. Greenfield, S. Dowland, V. Gray, S. T. J. Ryan, S. De Ornellas, A. H. El-Sagheer, T. Brown, J. R. Nitschke, J. Behrends, U. F. Keyser, A. Rao, R. Collepardo-Guevara, E. Stulz, R. H. Friend, and F. Auras.
Deoxyribonucleic Acid Encoded and Size-Defined p-Stacking of Perylene Diimides.
J. Am. Chem. Soc., 144(1):268-376, 2022. [ DOI | http ]

E. Kreysing, J. Mc Hugh, S. K. Foster, K. Andresen, R. D. Greemhalgh, E. K. Pillai, A. Dimitracopouos, U. F. Keyser, and K. Franze.
Effective cell membrane tension is independent of polyacrylamide substrate stiffness .
PNAS Nexus, 2(1): pgac299, 2022. [ DOI | http ]

D. Morzy, H. Joshi, S. E. Sandler, A. Aksimentiev, and U. F. Keyser.
Membrane activity of a DNA-based ion channel depends on the stability of its double-stranded structure.
Nano Letters, 21(22):9789-9796, 2021. [ DOI | http ]

R. Tivony, M. Fletcher, K. Al Nahas, and U. F. Keyser.
A Microfluidic Platform for Sequential Assembly and Separation of Synthetic Cell Models.
ACS Synth. Biol., 10(11):3105-3116, 2021. [ DOI | http ]

S. E. Ochmann, H. Joshi, E. Bueber, H. H. Franquelim, P. Stegemann, B. Sacca, U. F. Keyser, A. Aksimentiev, and P. Tinnefeld.
DNA Origami Voltage Sensors for Transmembrane Potentials with Single-Molecule Sensitivity.
Nano Letters, 21(20):8634-8641, 2021. [ DOI | http ]

J. Zhu, Z. Yan, F. Bošković, C.J.E. Haynes, M. Kieffer, J. L. Greenfield, J. Wang, J. R. Nitschke, and U. F. Keyser.
FeII4L4 tetrahedron binds and aggregates DNA G-quadruplexes.
Chemical Science, 12:14564-14569, 2021. [ DOI | http ]

J. Gladrow, U. F. Keyser, R. Adhikari, and J. Kappler.
Experimental Measurement of Relative Path Probabilities and Stochastic Actions.
Physical Review X, 11:031022, 2021. [ DOI | http ]

S. F. Knowles, N. E. Weckman, V. J. Lim, D. J. Bonthuis, U. F. Keyser, and A. L. Thorneywork.
Current Fluctuations in Nanopores Reveal the Polymer-Wall Adsorption Potential.
Physical Review Letters, 127:137801, 2021. [ DOI | .pdf ]

K. Al Nahas and U. F. Keyser.
Standardizing characterization of membrane active peptides with microfluidics.
Biomicrofluidics, 15:041301, 2021. [ DOI | http ]

K. Chen, I. Jou, N. Ermann, M. Muthukumar, U. F. Keyser, and N. A. W. Bell.
Dynamics of driven polymer transport through a nanopore.
Nature Physics, 17(9):1043-1049, 2021. [ DOI | http ]

J. Zhu, N. Ermann, K. Chen, and U. F. Keyser.
Image Encoding Using Multi-Level DNA Barcodes with Nanopore Readout.
Small, 17:2100711, 2021. [ DOI | http ]

D. Morzy, R. Rubio-Sanches, H. Joshi, A. Aksimentiev, L. di Michele, and U. F. Keyser.
Cations regulate membrane-attachment and functionality of DNA nanostructures.
JACS, 143(19):7358-7367, 2021. [ DOI | http ]

S. Tottori, K. Misiunas, V. Tshitoyan, and U. F. Keyser.
Channel-Length Dependence of Particle Diffusivity in Confinement (inside cover article).
Soft Matter, 17:5131-5136, 2021. [ DOI | http ]

K. Hammond, F. Cipcigan, K. Al Nahas, V. Losasso, H. Lewis, J. Cama, F. Martelli, P. Simcock, M. Fletcher, F. Stansfeld, S. Pagliara, B. Hoogenboom, U. F. Keyser, M. Sansom, J. Crain, and M. Ryadnov.
Switching Cytolytic Nanopores into Antimicrobial Fractal Ruptures by a Single Side Chain Mutation.
ACS nano, 15(6):9679-9689, 2021. [ DOI | http ]

F. Bošković, A. Ohmann, U. F. Keyser, and K. Chen.
DNA structural barcode copying and random access.
Small Structures, 2(5):2000144, 2021. [ DOI | http ]

K. Chen, F. Gularek, B. Liu, E. Weinhold, and U. F. Keyser.
Electrical DNA Sequence Mapping Using Oligodeoxynucleotide Labels and Nanopores.
ACS nano, 15(12):2679-2685, 2021. [ DOI | http ]

M. Caglar and U. F. Keyser.
Ionic and molecular transport in aqueous solution through 2D and layered nanoporous membranes.
Journal of Physics D: Applied Physics, 54:183002, 2021. [ DOI | http ]

J. Zhu, F. Bošković, B. N. T. Nguyen, J. R. Nitschke, and U. F. Keyser.
FeII4L4 tetrahedron binding controls the kinetics of toehold-mediated DNA strand displacement.
Nano Letters, 21(3):1368-1374, 2021. [ DOI | http ]

R. Chikkaraddy, V. A. Turek, Q. Lin, J. Griffiths, B. de Nijs, U. F. Keyser, and J. J. Baumberg.
Dynamics of deterministically positioned single-bond surface-enhanced Raman scattering from DNA origami assembled in plasmonic nanogaps.
Journal of Raman Spectroscopy, Special Issue:1-7, 2020. [ DOI | http ]

D. Sobota, H. Joshi, A. Ohmann, A. Aksimentiev, and U. F. Keyser.
Tailoring interleaflet lipid transfer with a DNA-based synthetic enzyme.
Nano Letters, 20(6):4306-4311, 2020. [ DOI | http ]

M. Schaich, D. Sobota, H. Sleath, J. Cama, and U. F. Keyser.
Biophysical characterization reveals the similarities of liposomes produced using microfluidics and electroformation.
Biochimica et Biophysica Acta (BBA)-Biomembranes, 1862:1833359, 2020. [ DOI | http ]

M. Chupeau, J. Gladrow, A. Chepelianskii, U. F. Keyser, and E. Trizac.
Optimizing Brownian escape rates by potential shaping.
Proceedings of the National Academy of Science, 117(3):1383-1388, 2020. [ DOI | http ]

J. Cama, M. Voliotis, J. Metz, A. Smith, J. Ianucci, U. F. Keyser, K. Tsaneva-Atanasova, and S. Pagliara.
Label-free single-cell microfluidics reveals antibiotic transport kinetics in Gram-negative bacteria.
Lab Chip, 20:2765-2775, 2020. [ DOI | http ]

A. Thorneywork, J. Gladrow, Y. Qing, M. Rico-Pasto, F. Ritort, H. Bayley, A. Kolomeisky, and U. F. Keyser.
Direct detection of molecular intermediates from first-passage times.
Science Advances, 6(18):eaaz4642, 2020. [ DOI | http ]

W. E. Arter, Y. Yusim, Q. Peter, C. G. Taylor, D. Klenerman, U. F. Keyser, and T. P. J. Knowles.
Digital Sensing and Molecular Computation by an Enzyme-Free DNA Circuit.
ACS Nano, 14(5):5763-5771, 2020. [ DOI | http ]

K. Chen, J. Zhu, F. Bošković, and U. F. Keyser.
Nanopore-Based DNA Hard Drives for Rewritable and Secure Data Storage.
Nano Letters, 5(5):3754-3760, 2020. [ DOI | http ]

M. Caglar, I. Silkene, B. T. Brown, A. L. Thorneywork, O. J. Burton, V. Babenko, S. M. Gilbert, A. Zettl, S. Hofmann, and U. F. Keyser.
Tunable Anion Selective Transport through Mono-Layer Graphene and Hexagonal Boron Nitride.
ACS nano, 14(3):2729-2738, published online (31/12/2019), 2020. [ DOI | http ]

N. Ćatić, L. Wells, K. Al Nahas, M. Smith, Q. Jing, U. F. Keyser, J. Cama, and S. Kar-Narayan.
Aerosol-jet printing facilitates the rapid prototyping of microfluidic devices with versatile geometries and precise channel functionalization.
Applied Materials Today, 19:100618, 2020. [ DOI | http ]

A. J. Plajer, J. Zhu, P. Prohm, F. J. Rizzuto, U. F. Keyser, and D. S. Wright.
Conformational Control in Main Group Phosphazane Anion Receptors and Transporters.
JACS, 142(2):1029-1037, 2020. [ DOI | http ]

S. Knowles, U. F. Keyser, and A. Thorneywork.
Noise properties of rectifying and non-rectifying nanopores.
Nanotechnology, 31:10LT01, 2020. [ DOI | http ]

M. Caglar, R. Pandya, J. Xiao, S. K. Foster, G. Divitini, R. Y. S. Chen, N. C. Greenham, K. Franze, A. Rao, and U. F. Keyser.
All-optical detection of neuronal membrane depolarization in live cells using colloidal quantum dots.
Nano Letters, 19(12):8539-8549, 2019. [ DOI | http ]

N. E. Weckman, R. Ermann, N. Gutierrez, K. Chen, J. Graham, A. Heron, and U. F. Keyser.
Pushing the resolution of dCas9 barcodes for multiplexed DNA identification with nanopore sensors.
IEEE sensors, online, 2019. [ DOI | http ]

A. Ohmann, K. Goepfrich, J. H. Himanshu, R. F. Thompson, D. Sobota, N. A. Ranson, A. Aksimentiev, and U. F. Keyser.
Controlling aggregation of cholesterol-modified DNA nanostructures.
Nucleic Acids Research, 47(21):11441-11451, 2019. [ DOI | http ]

F. Bošković, J. Zhu, K. Chen, and U. F. Keyser.
Monitoring G-Quadruplex Formation with DNA Carriers and Solid-State Nanopores.
Nano Letters, 19(11):7996-8001, 2019. [ DOI | http ]

O. Vanderpoorten, Q. Peter, P. Challa, U. F. Keyser, J. J. Baumberg, C. Kamsinski, and T. P. Knowles.
Scalable integration of nano-, and microfluidics with hybrid 2-photon lithography.
Microsystems & Nanoengineering, 5:40, 2019. [ DOI | http ]

N. E. Weckman, R. Ermann, N. Gutierrez, K. Chen, J. Graham, A. Heron, and U. F. Keyser.
Multiplexed DNA identification using site specific dCas9 barcodes and nanopore sensing.
ACS sensors, 4(8):2065-2072, 2019. [ DOI | http ]

J. Mc Hugh, K. Andresen, and U. F. Keyser.
Cation dependent electroosmotic flow in glass nanopores.
Applied Physics Letters, 115(11):113702, 2019. [ DOI | http ]

J. Zhu, C. J. E. Haynes, M. Kieffer, J. L. Greenfield, R. D. Greenhalgh, J. R. Nitschke, and U. F. Keyser.
FeII4L4 Tetrahedron Binds to Nonpaired DNA Bases.
JACS, 141(29):11358-11362, 2019. [ DOI | http ]

V. V. Wang, N. Ermann, and U. F. Keyser.
Current enhancement in solid-state nanopores depends on three-dimensional DNA structure.
Nano Letters, 19(8):5661-5666, 2019. [ DOI | http ]

S. Tottori, K. Misiunas, U. F. Keyser, and D. J. Bonthuis.
Nonlinear electrophoresis of highly charged nonpolarizable particles.
Physical Review Letters, 123:014502, 2019. [ DOI | http ]

K. Misiunas and U. F. Keyser.
Density dependent speed-up of particle transport in channels.
Physiscal Review Letters, 122:214501, 2019. [ DOI | http ]

A. J. Plajer, J. Zhu, P. Proehm, A. D. Bond, U. F. Keyser, and D. S. Wright.
Tailoring the Binding Properties of Phosphazane Anion Receptors and Transporters.
JACS, 141(22):8807-8815, 2019. [ DOI | http ]

M. Schaich, J. Cama, K. Al Nahas, D. Sobota, K. Jahnke, S. Deshpande, C. Dekker, and U. F. Keyser.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes.
Mol. Pharmaceutics, 16(6):2494-2501, 2019. [ DOI | http ]

S. Zarkan, S. Cano-Muniz, J. Zhu, K. Al Nahas, J. Cama, U. F. Keyser, and D. K. Summers.
Indole Pulse Signalling Regulates the Cytoplasmic pH of E. coli in a Memory-Like Manner.
Scientific Reports, 9:3868, 2019. [ DOI | http ]

O. S. Ojambati, R. Chikkaraddy, W. D. Deacon, M. Horton, D. Kos, V. A. Turek, U. F. Keyser, and J. J. Baumberg.
Quantum electrodynamics at room temperature coupling a single vibrating molecule with a plasmonic nanocavity.
Nature Communications, 10:1049, 2019. [ DOI | http ]

K. Al Nahas, J. Cama, K. Schaich, M. amd Hammond, S. Deshpande, C. Dekker, M. Ryadnov, and U. F. Keyser.
A microfluidic platform for the characterisation of membrane active antimicrobials.
Lab on a Chip, 19:837-844, 2019. [ DOI | http ]

K. Chen, J. Kong, J. Zhu, N. Ermann, P. Predki, and U. F. Keyser.
Digital Data Storage Using DNA Nanostructures and Solid-State Nanopores.
Nano Letters, 19(2):1210-1215, 2018. [ DOI | http ]

J. Gladrow, M. Ribezzi-Crivellari, F. Ritort, and U. F. Keyser.
Experimental evidence for symmetry breaking of transition path times.
Nature Communications, 10:55, 2018. [ DOI | http ]

J. Kong, J. Zhu, K. Chen, and U. F. Keyser.
Specific Biosensing Using DNA Aptamers and Nanopores.
Adv. Funct. Mater., 29:1807555, 2019. [ DOI | http ]

N. Ermann, N. Hanikel, V. Wang, K. Chen, and U. F. Keyser.
Promoting single-file DNA translocations through nanopores using electroosmotic flow.
The Journal of Chemical Physics, 149:163311, 2018. [ DOI | http ]

W. E. Arter, J. Charmet, J. Kong, K. L. Saar, T. W. Herling, T. Muller, U. F. Keyser, and T. P. J. Knowles.
Combining affinity selection and specific ion mobility for microchip protein sensing.
Analytical Chemistry, 90(17):10302-10310, 2018. [ DOI | http ]

A. Ohmann, C.-Y. Li, C. Maffeo, K Al Nahas, K. N. Baumann, K. Göpfrich, J. Yoo, U. F. Keyser, and A. Aksimentiev.
A synthetic enzyme built from DNA flips 10⁷ lipids per second in biological membranes.
Nature Communications, 9:2426, 2018. [ DOI | http ]

V. Turek, R. Chikkaraddy, S. Cormier, B. Stockham, T. Ding, U. F. Keyser, and J. J. Baumberg.
Thermo-responsive Actuation of a DNA Origami Flexor.
Adv. Funct. Mater., 28(25):1706410, 2018. [ DOI | http ]

K. Misiunas, N. Ermann, and U. F. Keyser.
QuipuNet: convolutional neural network for single-molecule nanopore sensing.
Nano Letters, 18(6):4040-4045, 2018. [ DOI | http ]

E. A. Hemmig, C. Fitzgerald, C. Maffeo, L. Hecker, S. E. Ochmann, A. Aksimentiev, P. Tinnefeld, and U. F. Keyser.
Optical voltage sensing using DNA origami.
Nano Letters, 18(3):1962-1971, 2018. [ DOI | http ]

V. Turek, S. Cormier, B. Sierra-Martin, U. F. Keyser, T. Ding, and J. J. Baumberg.
The Crucial Role of Charge in Thermoresponsive-Polymer-Assisted Reversible Dis/Assembly of Gold Nanoparticles.
Adv. Optical Mater., 6(8):1701270, 2018. [ DOI | http ]

R. Chikkaraddy, V. A. Turek, N. Kongsuwan, F. Benz, C. Carnegie, T. van de Goor, B. de Nijs, A. Demetriadou, O. Hess, U. F. Keyser, and J. J. Baumberg.
Mapping Nanoscale Hotspots with Single-Molecule Emitters Assembled into Plasmonic Nanocavities Using DNA Origami.
Nano Letters, 18(1):405-411, 2018. [ DOI | http ]

C. J. E. Haynes, J. Zhu, C. Chimerel, S. Hernandez-Ainsa, I. A. Riddell, T. K. Ronson, U. F. Keyser, and J. R. Nitschke.
Blockable Zn10L15 ion channels via subcomponent self-assembly.
Angewandte Chemie International Edition, 56(48):15388-15392, 2017. [ DOI | http ]

Y. Tan, L. Dagdug, J. Gladrow, U. F. Keyser, and S. Pagliara.
Particle transport across a channel via an oscillating potential.
Physical Review E, 96:052401, 2017. [ DOI | http ]

N. Kongsuwan, A. Demetriadou, R. Chikkaraddy, F. Benz, V. A. Turek, U. F. Keyser, J. J. Baumberg, and O. Hess.
Suppressed Quenching and Strong-Coupling of Purcell-Enhanced Single-Molecule Emission in Plasmonic Nanocavities.
ACS photonics, 5(1):186-191, 2018. [ DOI | http ]

N. A. W. Bell, K. Chen, S. Ghosal, M. Ricci, and U. F. Keyser.
Asymmetric dynamics of DNA entering and exiting a strongly confining nanopore.
Nature Communications, 8:380, 2017. [ DOI | http ]

K. Chen, M. Juhasz, F. Gularek, E. Weinhold, T. Yu, U. F. Keyser, and N. A. W. Bell.
Ionic Current-Based Mapping of Short Sequence Motifs in Single DNA Molecules using Solid-State Nanopores.
Nano Letters, 17(9):5199-5205, 2017. [ DOI | http ]

K. Chen, N. A. W. Bell, J. Kong, Y. Tian, and U. F. Keyser.
Direction- and Salt-Dependent Ionic Current Signatures for DNA Sensing with Asymmetric Nanopores.
Biophysical Journal, 112(4):674-682, 2017. [ DOI | http ]

M. I. Walker, K. Ubych, V. Saraswat, E. A. Chalklen, P. Braeuninger-Weimer, S. Caneva, R. S. Weatherup, S. Hofmann, and U. F. Keyser.
Extrinsic Cation Selectivity of 2D Membranes.
ACS nano, 11(2):1340-1346, 2017. [ DOI | http ]

A. C. Hodgson, C. V. Verstreken, C. L. Fisher, U. F. Keyser, S. Pagliara, and K. J. Chalut.
A microfluidic device for characterizing nuclear deformations.
Lab Chip, 17:805-813, 2017. [ DOI | http ]

J. Kong, J. Zhu, and U. F. Keyser.
Single Molecule Based SNP Detection Using Designed DNA Carriers and Solid-State Nanopores.
Chem. Commun., 53:436-439, 2017. [ DOI | http ]

J. Cama, M. Schaich, K. Al Nahas, S. Hernández-Ainsa, S. Pagliara, and U. F. Keyser.
Direct Optofluidic Measurement of the Lipid Permeability of Fluoroquinolones.
Scientific Reports, 6:32824, 2016. [ DOI | http ]

G. Rempfer, S. Ehrhardt, N. Laohakunakorn, G. B. Davies, U. F. Keyser, C. Holm, and J. de Graff.
Selective Trapping of DNA using Glass Microcapillaries.
Langmuir, 32(33):8525-8532, 2016. [ DOI | http ]

K. Göpfrich, C.-Y. Li, M. Ricci, S. P. Bhamidimarri, J. Yoo, B. Gyenes, A. Ohmann, M. Winterhalter, A. Aksimentiev, and U. F. Keyser.
Large-Conductance Transmembrane Porin Made from DNA Origami.
ACS nano, 10(9):8207-8214, 2016. [ DOI | http ]

L. Weller, V. V. Thacker, L. O. Herrmann, E. A. Hemmig, A. Lombardi, U. F. Keyser, and J. J. Baumberg.
Gap-dependent plasmonic coupling of Ag-Au nanoparticle heterodimers using DNA origami-based self-assembly.
ACS Photonics, 3(9):1589-1595, 2016. [ DOI | http ]

S. Tesoro, K. Göpfrich, T. Kartanas, U. F. Keyser, and S. E. Ahnert.
Nondeterministic self-assembly with asymmetric interactions.
Physical Review E, 94(2):022404, 2016. [ DOI | http ]

S. Hernández-Ainsa, M. Ricci, L. Hilton, A. Avino, R. Eritja, and U. F. Keyser.
Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA.
Nano Letters, 16(7):4462-4466, 2016. [ DOI | http ]

K. Göpfrich, C.-Y. Li, I. Mames, S. P. Bhamidimarri, M. Ricci, J. Yoo, A. Mames, A. Ohmann, M. Winterhalter, E. Stulz, A. Aksimentiev, and U. F. Keyser.
Ion Channels Made from a Single Membrane-Spanning DNA Duplex.
Nano Letters, 16(7):4665-4669, 2016. [ DOI | http ]

J. Kong, N. A. W. Bell, and U. F. Keyser.
Quantifying Nanomolar Protein Concentrations Using Designed DNA Carriers and Solid-State Nanopores.
Nano Letters, 16(6):3557-3562, 2016. [ DOI | http ]

N. A. W. Bell and U. F. Keyser.
Digitally encoded DNA nanostructures for multiplexed, single-molecule protein sensing with nanopores.
Nature Nanotechnology, 11:645-651, 2016. [ DOI | .html ]

S. Purushothaman, J. Cama, and U. F. Keyser.
Dependence of Norfloxacin diffusion across bilayers on lipid composition.
Soft Matter, 12:2135-2144, 2016. [ DOI | http ]

E. A. Hemmig, C. Creatore, B. Wünsch, L. Hecker, P. Mair, M. A. Parker, S. Emmott, P. Tinnefeld, U. F. Keyser, and A. W. Chin.
Programming light-harvesting efficiency using DNA origami.
Nano Letters, 16(4):2369-2374, 2016. [ DOI | http ]

U. F. Keyser.
Enhancing nanopore sensing with DNA nanotechnology - Commentary.
Nature Nanotechnology, 11:106-108, 2016. [ DOI | .html ]

N. A. W. Bell, M. Muthukumar, and U. F. Keyser.
Translocation frequency of double-stranded DNA through a solid-state nanopore.
Physical Review E, 93:022401, 2016. [ DOI | http ]

M. I. Walker, P. Braeuninger-Weimar, R. S. Weatherup, S. Hofmann, and U. F. Keyser.
Measuring the Proton Selectivity of Graphene Membranes.
Applied Physics Letters, 107:213104, 2015. [ DOI | http ]

J. Cama, H. Bajaj, S. Pagliara, T. Maier, Y. Braun, M. Winterhalter, and U. F. Keyser.
Quantification of fluoroquinolone uptake through the outer membrane channel OmpF of Escherichia coli.
JACS, 137(43):13836-13843, 2015. [ DOI | http ]

N. Laohakunakorn and U. F. Keyser.
Electroosmotic flow rectification in conical nanopores.
Nanotechnology, 26(27):275202, 2015. [ DOI | http ]

N. Martyushenko, N. A. W. Bell, R. Lamboll, and U. F. Keyser.
Nanopore analysis of amyloid fibrils formed by lysozyme aggregation.
Analyst, 140:4882-4886, 2015. [ DOI | http ]

K. Misiunas, S. Pagliara, E. Lauga, J. R. Lister, and U. F. Keyser.
Nondecaying hydrodynamic interactions along narrow channels.
Physical Review Letters, 115:038301, 2015. [ DOI | http ]

K. Göpfrich, T. Zettl, A. E. C. Meijering, S. Hernández-Ainsa, S. Kocabey, T. Liedl, and U. F. Keyser.
DNA-Tile Structures Induce Ionic Currents through Lipid Membranes.
Nano Letters, 15(5):3134-3138, 2015. [ DOI | http ]

N. A. W. Bell and U. F. Keyser.
Specific Protein Detection using Designed DNA Carriers and Nanopores.
JACS, 137(5):2035-2041, 2015. [ DOI | http ]

O. Otto, P. Rosendahl, A. Mietke, S. Golfier, C. Herold, D. Klaue, S. Girardo, S. Pagliara, A. Ekpenyong, A. Jakobi, M. Wobus, N. Töpfner, U. F. Keyser, J. Mansfeld, E. Fischer-Friedrich, and J. Guck.
Real-time deformability cytometry: High-throughput cell mechanical phenotyping on-the-fly.
Nature Methods, 12:199-202, 2015. [ DOI | .html ]

C.-Y. Li, E. A. Hemmig, J. Kong, J. Yoo, S. Hernández-Ainsa, U. F. Keyser, and A. Aksimentiev.
Ionic Conductivity, Structural Deformation and Programmable Anisotropy of DNA Origami in Electric Field.
ACS nano, 9(2):1420-1433, 2015. [ DOI | http ]

M. I. Walker, R. S. Weatherup, N. A. W. Bell, S. Hofmann, and U. F. Keyser.
Free-standing graphene membranes on glass nanopores for ionic current measurements.
Applied Physics Letters, 106:023119, 2015. [ DOI | http ]

A. Seifert, K Goepfrich, J. Burns, N. Fertig, U. F. Keyser, and S. Howorka.
Bilayer-spanning DNA nanopores with voltage-switching between open and closed state.
ACS nano, 9(2):1117-1126, 2015. [ DOI | http ]

A. Huhle, D. Klaue, H. Brutzer, D. Daldrop, O. Otto, U. F. Keyser, and R. Seidel.
Camera-based three-dimensional real-time particle tracking at kHz rates and Angstrom accuracy.
Nature Communications, 6:5885, 2015. [ DOI | .html ]

T. Gutsmann, T. Heimburg, U. F. Keyser, K. R. Mahendran, and M. Winterhalter.
Protein reconstitution into free standing planar lipid membranes for electrophysiological characterization.
Nature Protocols, 10:188-198, 2015. [ DOI | .html ]

N. Laohakunakorn, V. V. Thacker, M. Muthukumar, and U. F. Keyser.
Electroosmotic flow reversal outside glass nanopores.
Nano Letters, 15(1):695-702, 2014. [ DOI | http ]

R. D. Bulushev, L. J. Steinbock, S. Khlybov, J. F. Steinbock, U. F. Keyser, and A. Radenovic.
Measurement of the position-dependent electrophoretic force on DNA in a glass nanocapillary.
Nano Letters, 14(11):6606-6613, 2014. [ DOI | http ]

S. Pagliara, S. L. Dettmer, K. Misiunas, L. Lea, Y. Tan, and U. F. Keyser.
Diffusion coefficients and particle transport in synthetic membrane channels.
European Physical Journal Special Topics, 223:3145, 2014. [ DOI | http ]

C. Chimerel, E. Emery, D. K. Summers, U. F. Keyser, F. M. Gribble, and F. Reimann.
Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells.
Cell Reports, 9(4):1202-1208, 2014. [ DOI | http ]

S. M. Hernández-Ainsa, , and U. F. Keyser.
DNA origami nanopores: developments, challenges and perspectives.
Nanoscale, 6:14121-14132, 2014. [ DOI | http ]

S. Pagliara, S. L. Dettmer, and U. F. Keyser.
Channel-facilitated diffusion boosted by particle binding at the channel entrance.
Physical Review Letters, 113:048102, 2014. [ DOI | http ]

N. A. W. Bell and U. F. Keyser.
Nanopores formed by DNA origami: a review.
FEBS Letters, 588(29):3564-3570, 2014. [ DOI | http ]

S. L. Dettmer, K. Misiunas, S. Pagliara, and U. F. Keyser.
Anisotropic diffusion of spherical particles in closely confining microchannels.
Physical Review E, 89:062305, 2014. [ DOI | http ]

J. Cama, C. Chimerel, S. Pagliara, A. Javer, and U. F. Keyser.
A label-free microfluidic assay to quantitatively study antibiotic diffusion through lipid membranes.
Lab Chip, 14:2303-2308, 2014. [ DOI | http ]

S. Pagliara, K. Franze, C. R. McClain, G. W. Wylde, C. L. Fisher, R. J. M. Franklin, A. J. Kabla, U. F. Keyser, and K. J. Chalut.
Auxetic nuclei in embryonic stem cells exiting pluripotency.
Nature Materials, 13:638-644, 2014. [ DOI | .html ]

O. J. Pambos and U. F. Keyser.
Giant unilamellar vesicles and suspended nanobilayers as model systems for biophysical research.
Advances in Planar Lipid Bilayers and Liposomes, 19:67-89, 2014. [ DOI | http ]

H. Gaimster, J. Cama, S. Hernández-Ainsa, U. F. Keyser, and D. K. Summers.
The indole pulse: a new perspective on indole signalling in escherichia coli.
PLoS ONE, 9(4):e93168, 2014. [ DOI | http ]

K. D. Schleicher, S. L. Dettmer, L. E. Kapinos, S. Pagliara, U. F. Keyser, S. Jeney, and R. Y. H. Lim.
Selective Transport Control on Molecular Velcro Made From Intrinsically Disordered Proteins.
Nature Nanotechnology, 9:525-530, 2014. [ DOI | .html ]

V.V. Thacker, L. O. Hermann, D. O. Sigle, T. Zhang, T. Liedl, J. J. Baumberg, and U. F. Keyser.
DNA origami based assembly of gold nanoparticle dimers for surface-enhanced Raman scattering.
Nature communications, 5:3448, 2014. [ DOI | .html ]

S. L. Dettmer, U. F. Keyser, and S. Pagliara.
Local characterization of hindered Brownian motion by using bright-field video microscopy and 3D particle tracking.
Rev. Sci. Instr., 85:023708, 2014. [ DOI | http ]

S. Hernández-Ainsa, K. Misiunas, V. V. Thacker, E. A. Hemmig, and U. F. Keyser.
Voltage dependent properties of DNA origami nanopores.
Nano Letters, 14(3):1270-1274, 2014. [ DOI | http ]

T. Yanagishima, N. Laohakunakorn, U. F. Keyser, E. Eiser, and H. Tanaka.
Influence of internal viscoelastic modes on the Brownian motion of a lambda-DNA coated colloid.
Soft Matter, 10:1738-1745, 2014. [ DOI | http ]

V. V. Thacker, K. Bromek, B. Meijer, J. Kotar, B. Sclavi, M. Cosentino Lagomarsino, U. F. Keyser, and P. Cicuta.
Bacterial nucleoid structure probed by active drag and resistive pulse sensing.
Integr. Biol., 6:184-191, 2014. [ DOI | http ]

N. Laohakunakorn, B. Gollnick, F. Moreno-Herreo, D. G. A. L. Aart, R. P. A Dullens, S. Ghosal, and U. F. Keyser.
A Landau-Squire nanojet.
Nano Letters, 13(11):5141-5146, 2013. [ DOI | http ]

O. Laohakunakorn, N. an dOtto, S. Sturm, K. Kroy, and U. F. Keyser.
Dynamic single-molecule force spectroscopy using optical tweezers and nanopores.
Proc. of SPIE, 8810:88101F, 2013. [ DOI | http ]

S. Hernández-Ainsa and U. F. Keyser.
DNA origami nanopores: an emerging tool in biomedicine (invited editorial).
Nanomedicine, 8(10):1551-1554, 2013. [ DOI | http ]

J. Sha, T. Hasan, S. Milana, C. Bertulli, N. A. W. Bell, G. Provotera, Z. Ni, Y. Chen, F. Bonaccorso, A. Ferrari, U. F. Keyser, and Y. Y. S. Huang.
Nanotubes Complexed with DNA and Proteins for Resistive-pulse Sensing.
ACS nano, 7(10):8857-8869, 2013. [ DOI ]

J. R. Burns, K. Goepfrich, J. W. Wood, V. V. Thacker, E. Stulz, U. F. Keyser, and S. Howorka.
Lipid-Bilayer-Spanning DNA Nanopores with a Bifunctional Porphyrin Anchor (published as HOT PAPER).
Angewandte Chemie International Edition, 52(46):12069-12072, 2013. [ DOI | http ]

S. Hernández-Ainsa, N. A. W. Bell, V. V. Thacker, K. Goepfrich, K. Misiunas, M. Fuentes-Perez, F. Moreno-Herrero, and U. F. Keyser.
DNA origami nanopores for controlling DNA translocation.
ACS nano, 7(7):6024-6030, 2013. [ DOI | http ]

N. Laohakunakorn, S. Ghosal, O. Otto, K. Misiunas, and U. F. Keyser.
DNA Interactions in Crowded Nanopores.
Nano Letters, 13(6):2798-2802, 2013. [ DOI | http ]

N. A. W. Bell, V. V. Thacker, S. Hernández-Ainsa, M. Fuentes-Perez, F. Moerno-Herrero, T. Liedl, and U. F. Keyser.
Multiplexed ionic current sensing with glass nanopores.
Lab on a Chip, 13:1859-1862, 2013. [ DOI ]

W. Li, N. A. W. Bell, S. Hernández-Ainsa, V. V. Thacker, A. M. Thackray, R. Bujdoso, and U. F. Keyser.
Single protein molecule detection by glass nanopores.
ACS nano, 7(5):4129-4134, 2013. [ DOI | http ]

O. Otto, S. Sturm, N. Laohakunakorn, U. F. Keyser, and K. Kroy.
Rapid internal contraction boosts DNA friction.
Nature Communication, 4, 2013. [ DOI | .html ]

S. Pagliara, C. Schwall, and U. F. Keyser.
Optimizing Diffusive Transport Through a Synthetic Membrane Channel.
Advanced Materials, 25 (published online 15/11/2012)(6):844-849, 2013. [ DOI | http ]

C. Chimerel, A. J. Murray, E. R. Olderwurtel, D. K. Summers, and U. F. Keyser.
The effect of bacterial signal indole on the electrical properties of lipid membranes.
ChemPhysChem, 14(2):417-423, 2013. [ DOI | http ]

K. Goepfrich, C. V. Kulkarni, O. Pambos, and U. F. Keyser.
Lipid Nanobilayers to Host Biological Nanopores for DNA Translocations.
Langmuir, 29(1):355-364, 2013. [ DOI | http ]

S. Hernández-Ainsa, C. Muus, N. A. W. Bell, L. J. Steinbock, V. V. Thacker, and U. F. Keyser.
Lipid-coated nanocapillaries for DNA sensing.
Analyst, 138:104-106, 2013. [ DOI | http ]

L. J. Steinbock, A. Lucas, O. Otto, and U. F. Keyser.
Salt dependent transport of ions and DNA through nanocapillaries.
Electrophoresis, 33:3480-3487, 2012. [ DOI | http ]

V. V. Thacker, S. Ghosal, S. Hernández-Ainsa, N. A. W. Bell, and U. F. Keyser.
Studying DNA translocation in nanocapillaries using single molecule fluorescence.
Applies Physics Letters, 101:223704, 2012. [ DOI | http ]

S. Ghosal.
Capstan Friction Model for DNA Ejection from Bacteriophages.
Physical Review Letters, 109:248105, 2012. [ DOI | http ]

V. Fodera, S. Pagliara, O. Otto, U. F. Keyser, and A. M. Donald.
Microfluidics Reveals a Flow-Induced Polymorphism of Protein Aggregates.
J. Phys. Chem. Lett., 3(19):2803-2807, 2012. [ DOI | http ]

A. Ekpenyong, G. Whyte, K. Chalut, S. Pagliara, F. Lautenschlager, C. Fiddler, S. Paschke, U. F. Keyser, E. R. Chilvers, and J. Guck.
Viscoelastic Properties of Differentiating Blood Cells are Fate- and Function-Dependent.
PLOS ONE, 7(9):e45237, 2012. [ DOI | http ]

U. F. Keyser.
Nanopores - mission accomplished and what next? Comment on "Nanopores: a journey towards DNA sequencing" by M. Wanunu.
Physics of Life Reviews, 9(2):164-166, 2012. [ DOI | http ]

C.-W. Lee, S. Pagliara, U. F. Keyser, and J. J. Baumberg.
Perpendicular coupling to in-plane photonics using arc waveguides fabricated via two-photon polymerization.
Applied Physics Letters, 100:171102, 2012. [ DOI | http ]

C. Chimerel, C. M. Field, S. Pinero-Fernandez, U. F. Keyser, and D. K. Summers.
Indole prevents Escherichia coli cell division by modulating membrane potential.
BBA - Biomembranes, 1818(7):1590-1594, 2012. [ DOI | http ]

N. A. W. Bell, C. R. Engst, M. Ablay, G. Divitini, C. Ducati, T. Liedl, and U. F. Keyser.
DNA origami nanopores.
Nano Letters (published online 20.12.2011), 12(1):512-517, 2012. [ DOI | http ]

U. F. Keyser.
Optical tweezers for mechanical control over DNA in a nanopore.
Methods Mol. Biol., 870:115-134, 2012.

L. J. Steinbock and U. F. Keyser.
Analyzing single DNA molecules by nanopore translocation.
Methods Mol. Biol., 870:135-145, 2012.

N. A. W. Bell, S. Hernández-Ainsa, C. Engst, T. Liedl, and U. F. Keyser.
Ionic current detection of DNA origami nanostructures with nanocapillaries.
RSC Proceedings, pages 1-4, 2012.

V. V. Thacker, S. Hernández-Ainsa, J. L. Gornall, L. J. Steinbock, and U. F. Keyser.
Combining fluorescence imaging and ionic current detection in nanocapillaries.
RSC Proceedings, pages 43-45, 2012. [ DOI ]

O. J. Pambos, K. Goepfrich, K. R. Mahendran, J. L. Gornall, O. Otto, L. J. Steinbock, C. Chimerel, M. Winterhalter, and U. F. Keyser.
Towards simultaneous force and resistive pulse sensing in protein nanopores using optical tweezers.
RSC Proceedings, pages 72-75, 2012. [ DOI ]

O. Otto, N. Laohakunakorn, L. J. Steinbock, and U. F. Keyser.
Forces on DNA in confinement as measured by optical tweezers.
RSC Proceedings, pages 62-66, 2012. [ DOI ]

L. J. Steinbock and U. F. Keyser.
Potential Dependence of DNA Translocation.
RSC Proceedings, pages 67-71, 2012. [ DOI ]

S. Pagliara, C. Chimerel, R. Langford, D. G. A. L. Aarts, and U. F. Keyser.
Colloid flow control in microchannels and detection by laser scattering.
Progr. Colloid Polym. Sci., 139:45, 2012. [ DOI | http ]

U. F. Keyser.
Self-Aware Particles.
Nature, 478:45, 2011. [ DOI ]

O. Otto, L. J. Steinbock, and U. F. Keyser.
Nanocapillaries and Optical Tweezers for Studies on DNA in Confinement.
Proc. of SPIE, 8097:80970B, 2011. [ DOI ]

L. J. Gornall, K. R. Mahendran, O. J. Pambos, L. J. Steinbock, O. Otto, C. Chimerel, M. Winterhalter, and U. F. Keyser.
Simple reconstitution of protein pores in nano lipid bilayers.
Nano Letters, 11(8):3334-3340, 2011. [ DOI | http ]

S. Pagliara, C. Chimerel, R. Langford, D. G. A. L. Aarts, and U. F. Keyser.
Sub-micrometer channels with tuneable cross section and laser scattering detection for microfluidics.
Lab on a Chip, 11(19):3365-3368, 2011. [ DOI ]

O. Otto, L. J. Steinbock, D. W. Wong, J. L. Gornall, and U. F. Keyser.
Note: Direct force and ionic-current measurements on DNA in a nanocapillary.
Review of Scientific Intruments, 82:086102, 2011. [ DOI | http ]

U. F. Keyser.
Controlling molecular transport through nanopores.
J. R. Soc. Interface, 8:1369-1378, 2011. [ DOI | http ]

O. Otto, J. L. Gornall, G. Stober, F. Czerwinski, R. Seidel, and U. F. Keyser.
High-Speed Video-Based Tracking of Optically Trapped Colloids.
Journal of Optics, 13(4):044011, 2011. [ DOI ]

S. Pinero-Fernandez, C. Chimerel, U.F. Keyser, and D.K. Summers.
Indole transport across Escherichia coli membranes.
J. Bacteriology, 193(8):1793-1798, 2011. [ DOI | http ]

C. Gutsche, M. M. Elmahdy, K. Kegler, I. Semenov, T. Stangner, O. Otto, O. Ueberschaer, U. F. Keyser, M. Krueger, M. Rauscher, R. Weeber, R. Harting, Y. W. Kim, V. Lobaskin, R. R. Netz, and F. Kremer.
Micro-rheology on (polymer-grafted) colloids using Optical Tweezers.
Journal of Physics: Condensed Matter, 23(18):184114, 2011. [ DOI | http ]

C. Wagner, C. Olbrich, H. Brutzer, M. Salomo, U. Kleinekathofer, U. F. Keyser, and F. Kremer.
DNA condensation by TmHU studied by optical tweezers, AFM and molecular dynamics simulations.
Journal of Biological Physics, 37(1):117-131, 2010. [ http ]

O. Otto, F. Czerwinski, J. L. Gornall, G. Stober, L. B. Oddershedde, R. Seidel, and U. F. Keyser.
Real-time Particle Tracking at 10,000 fps using Optical Fiber Illumination.
Optics Express, 18(22):22722-227733, 2010. [ DOI | http ]

O. Otto, F. Czerwinski, J. L. Gornall, G. Stober, L. B. Oddershedde, R. Seidel, and U. F. Keyser.
Supplementary Material for: Real-time Particle Tracking at 10,000 fps using Optical Fiber Illumination.
Optics Express, 18(22):22722-227733, 2010. [ .pdf ]

L. J. Steinbock, O. Otto, C. Chimerel, J. Gornall, and U. F. Keyser.
Detecting DNA Folding with Nanocapillaries.
Nano Letters, 10(7):2493-2497, 2010. [ DOI | http ]

U. F. Keyser.
DNA Tug of War: Tether forces on DNA in a nanopore.
Proc. of SPIE, 7762:776204, 2010. [ DOI ]

O. Otto and F. Czerwinski.
Observing and Controlling Biomolecules with Optical Tweezers and LabVIEW.
National Instruments - Labview Case Studies, 2010. [ http ]

L. J. Steinbock, O. Otto, D. R. Skarstam, S. Jahn, C. Chimerel, J. L. Gornall, and U. F. Keyser.
Probing DNA with Micro- and Nanocapillaries and Optical Tweezers.
Journal of Physics: Condensed Matter, 22(45):454113, 2010. [ DOI | http ]

U. F. Keyser, S. Van Dorp, and S. G. Lemay.
Tether forces in DNA electrophoresis.
Chemical Society Reviews, 39:939 - 947, 2010. [ DOI | http ]

L. J. Steinbock, G. Stober, and U. F. Keyser.
Sensing DNA-coatings of microparticles using micropipettes.
Biosensors & Bioelectronics, 24(8):2423-7, 2009. [ DOI ]

G. Stober, L. J. Steinbock, and U. F. Keyser.
Modeling of colloidal transport in capillaries.
Journal of Applied Physics, 105(8):084702, 2009. [ DOI ]

B. Wunderlich, C. Leirer, A.-L. Idzko, U. F. Keyser, A. Wixforth, V. M. Myles, T. Heimburg, and M. F. Schneider.
Phase state dependent current fluctuations in pure lipid membranes.
Biophysical Journal, 96:4592, 2009. [ DOI | http ]

S. van Dorp, U. F. Keyser, N. H. Dekker, C. Dekker, and S. G. Lemay.
Origin of the electrophoretic force in nanopores.
Nature Physics, 5:347, 2009. [ DOI | http ]

U. F. Keyser, J. van der Does, C. Dekker, and N. H. Dekker.
Methods in Molecular Biology 544, chapter 8: Inserting and Manipulating DNA in a Nanopore with Optical Tweezers, pages 95-112.
Springer Protocols, Humana Press (Dordrecht), 2009. [ DOI ]

I. Semenov, O. Otto, G. Stober, P. Papadopoulos, U. F. Keyser, and F. Kremer.
Single colloid electrophoresis.
Journal of Colloid and Interface Science, 337:260-264, 2009. [ DOI ]

O. Otto, C. Gutsche, F. Kremer, and U. F. Keyser.
Optical tweezers with 2.5 kHz bandwidth video detection for single-colloid electrophoresis.
The Review of Scientific Instruments, 79:023710, 2008. [ DOI ]

Publications before I started my lab at Cambridge 2007-1999

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